CPC G01N 21/4738 (2013.01) [A61B 5/14532 (2013.01); G06N 20/00 (2019.01); G06T 7/0012 (2013.01)] | 14 Claims |
1. A method of transforming Monte Carlo (MC) simulations for diffuse reflectance spectroscopy (DRS), the method comprising:
obtaining, by a DRS device, MC simulated DRS measurements using a pre-defined number of photons;
pre-processing, by the DRS device, the MC simulated DRS measurements to obtain normalized DRS measurements;
correcting, by the DRS device, non-monotonicity of the normalized DRS measurements to obtain monotonic DRS measurements;
converting, by the DRS device, the monotonic DRS measurements to a logarithmic domain to obtain logarithmic DRS measurements;
performing, by the DRS device, curve fitting on the logarithmic DRS measurements in the logarithmic domain to obtain curve-fitted logarithmic DRS measurements; and
transforming, by the DRS device, the curve-fitted logarithmic DRS measurements to a non-logarithmic domain to obtain transformed MC simulated DRS measurements,
wherein the correcting of non-monotonicity of the normalized DRS measurements is performed using an isotonic regression technique.
|