US 11,814,511 B2
Hydrogel composition, tissue model, and manufacturing method for tissue model
Makoto Ohta, Sendai (JP); Yasutomo Shimizu, Sendai (JP); and Ren Takahashi, Sendai (JP)
Assigned to TOHOKU UNIVERSITY, Sendai (JP)
Appl. No. 16/640,881
Filed by TOHOKU UNIVERSITY, Sendai (JP)
PCT Filed Aug. 21, 2018, PCT No. PCT/JP2018/030844
§ 371(c)(1), (2) Date Feb. 21, 2020,
PCT Pub. No. WO2019/039473, PCT Pub. Date Feb. 28, 2019.
Claims priority of application No. 2017-158316 (JP), filed on Aug. 21, 2017.
Prior Publication US 2020/0354557 A1, Nov. 12, 2020
Int. Cl. G09B 23/30 (2006.01); C08L 29/04 (2006.01)
CPC C08L 29/04 (2013.01) [G09B 23/30 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A hydrogel composition for a tissue model, the hydrogel composition comprising a polyvinyl alcohol and a pseudoplastic compound,
wherein a Young's modulus at a strain of 0.5 of the hydrogel composition is 160 to 700 kPa,
wherein a content of the polyvinyl alcohol in the hydrogel composition is 13 to 20 weight percent and a content of the pseudoplastic compound in the hydrogel composition is more than 0 weight percent and 0.5 weight percent or less; and
wherein a dynamic viscosity of a solution including the polyvinyl alcohol and the pseudoplastic compound prepared before the production of the hydrogel composition is 16.6 Pa·s to 40.8 Pa·s at a shear rate of 6 to 170 sec−1.