US 11,814,445 B2
Cyclic polypeptides for PCSK9 inhibition
Alonso Ricardo, Cambridge, MA (US); Nicolas Cedric Boyer, Somerville, MA (US); Joseph R. Stringer, Winchester, MA (US); Derek M. LaPlaca, Somerville, MA (US); Kelli Jette, Somerville, MA (US); and Yili Sun, Dracut, MA (US)
Assigned to Ra Pharmaceuticals, Inc., Cambridge, MA (US)
Appl. No. 17/253,774
Filed by Ra Pharmaceuticals, Inc., Cambridge, MA (US)
PCT Filed Jun. 20, 2019, PCT No. PCT/US2019/038221
§ 371(c)(1), (2) Date Dec. 18, 2020,
PCT Pub. No. WO2019/246387, PCT Pub. Date Dec. 26, 2019.
Claims priority of provisional application 62/688,037, filed on Jun. 21, 2018.
Prior Publication US 2022/0089640 A1, Mar. 24, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/02 (2006.01); A61K 38/00 (2006.01)
CPC C07K 7/02 (2013.01) [A61K 38/00 (2013.01)] 15 Claims
 
1. A cyclic peptide compound selected from the group consisting of:

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