CPC C07K 16/2818 (2013.01) [A01K 67/0278 (2013.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C12N 15/85 (2013.01); G01N 33/6803 (2013.01); A01K 2227/105 (2013.01); A61K 2039/505 (2013.01); C07K 16/18 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01)] | 10 Claims |
1. An isolated single domain antibody that binds to human PD-1 but does not block the interaction of human PD-1 with human PD-L1 and/or PD-L2, wherein said single domain antibody is a human heavy chain variable domain (VH) comprising a CDR1, 2, and 3 having the following sequences SEQ ID NOs: 173, 174, and 175, respectively.
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