US 11,814,424 B2
Anti-varicella-zoster virus antibody, immunological measurement method, and immunological measurement device
Hisahiko Iwamoto, Kanagawa (JP); Keita Suzuki, Kanagawa (JP); and Tetsuo Tomiyama, Tokyo (JP)
Assigned to TANAKA KIKINZOKU KOGYO K.K., Tokyo (JP)
Filed by TANAKA KIKINZOKU KOGYO K.K., Tokyo (JP)
Filed on Apr. 26, 2021, as Appl. No. 17/240,580.
Claims priority of application No. 2020-078713 (JP), filed on Apr. 27, 2020.
Prior Publication US 2021/0332109 A1, Oct. 28, 2021
Int. Cl. A61K 39/42 (2006.01); C07K 16/08 (2006.01); G01N 33/569 (2006.01)
CPC C07K 16/088 (2013.01) [G01N 33/56994 (2013.01); C07K 2317/565 (2013.01)] 2 Claims
 
1. An immunological measurement device for detecting Varicella-zoster virus (VZV), comprising a sample addition part, a labeling substance retaining part, a chromatographic medium part having a detection part, and an absorption part, and wherein the labeling substance retaining part and the detection part are the following (i) or (ii):
(i) the labeling substance retaining part contains a labeling substance and an antibody of (1a) below bound to the labeling substance, and the detection part contains an antibody of (2a) below; or
(ii) the labeling substance retaining part contains a labeling substance and an antibody of (2a) below bound to the labeling substance, and the detection part contains an antibody of (1a) below:
(1a) an antibody in which the amino acid sequences of CDRs 1 to 3 of VH contain the amino acid sequences represented by SEQ ID NOS: 8, 9, and 10, respectively, and the amino acid sequences of CDRs 1 to 3 of VL contain the amino acid sequences represented by SEQ ID NOS: 11, 12, and 13, respectively;
(2a) an antibody in which the amino acid sequences of CDRs 1 to 3 of VH of the antibody contain the amino acid sequences represented by SEQ ID NOS: 14, 15, and 16, respectively, and the amino acid sequences of CDRs 1 to 3 of VL of the antibody contain the amino acid sequences represented by SEQ ID NOS: 17, 18, and 19, respectively.