	US 11,814,334 B2
	Separation of basic amino acids
Torgny Näsholm, Umeå (SE); Jonathan Love, Umeå (SE); Mattias Holmlund, Umeå (SE); and Nils Bertil Skoglund, Vännäsby (SE)
Assigned to AREVO AB, Umeå (SE)
Appl. No. 16/976,918
Filed by AREVO AB, Umeå (SE)
PCT Filed Mar. 5, 2019, PCT No. PCT/SE2019/050188 § 371(c)(1), (2) Date Aug. 31, 2020, PCT Pub. No. WO2019/172825, PCT Pub. Date Sep. 12, 2019.
Claims priority of application No. 1850233-6 (SE), filed on Mar. 5, 2018.
Prior Publication US 2021/0017122 A1, Jan. 21, 2021
Int. Cl. C07C 227/42 (2006.01); C05B 15/00 (2006.01); C07C 277/08 (2006.01)

CPC C07C 227/42 (2013.01) [C05B 15/00 (2013.01); C07C 277/08 (2013.01)]

16 Claims

1. A method of separating arginine or lysine from an aqueous solution, which method comprises

a) providing an aqueous solution comprising amino acids as well as proteins and/or protein decomposition products;

b) combining the aqueous solution with phosphoric acid;

c) maintaining the aqueous solution including phosphoric acid at room temperature until a precipitate of amino acid phosphate is obtained, wherein the amino acid phosphate is selectively precipitated as a monophosphate of arginine or lysine;

d) separating said precipitate from the aqueous solution; and

e) redissolving the separated precipitate into an aqueous solution of amino acid and phosphate.