CPC A61K 9/7069 (2013.01) [A61K 9/7053 (2013.01); A61K 31/407 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 9/7061 (2013.01); A61K 47/12 (2013.01)] | 20 Claims |
1. A patch, comprising:
a support layer; and
an adhesive agent layer formed on the support layer and comprising asenapine and/or a pharmaceutically acceptable salt thereof, a maleic acid alkali salt, and a rubber-based adhesive agent such that a content of the maleic acid alkali salt in the adhesive agent layer is in a range of 1% by mass to 10% by mass,
wherein the adhesive agent layer includes free asenapine derived from the asenapine and/or pharmaceutically acceptable salt thereof such that a content of the free asenapine in the adhesive agent layer is in a range of 2% by mass to 10% by mass and that a mass ratio of the free asenapine to the rubber-based adhesive agent is in a range of 1:17 to 1:1.2.
|