US 11,813,293 B2
Fat-depleted adipose tissue and a device and method for preparing the same
Samer Srouji, Haifa (IL)
Assigned to Samer Srouji, Haifa (IL); and Zohar Gendler, Zichron-Yaakov (IL)
Filed by Samer Srouji, Haifa (IL); and Zohar Gendler, Zichron-Yaakov (IL)
Filed on Jul. 28, 2021, as Appl. No. 17/387,580.
Application 17/387,580 is a division of application No. 15/571,432, granted, now 11,077,235, previously published as PCT/IL2016/050474, filed on May 5, 2016.
Claims priority of provisional application 62/156,935, filed on May 5, 2015.
Prior Publication US 2021/0353847 A1, Nov. 18, 2021
Int. Cl. B30B 9/04 (2006.01); B30B 15/22 (2006.01); A61K 35/28 (2015.01); A61K 35/32 (2015.01); A61K 35/35 (2015.01); A61M 1/00 (2006.01); B30B 9/06 (2006.01); B30B 15/08 (2006.01)
CPC A61K 35/28 (2013.01) [A61K 35/32 (2013.01); A61K 35/35 (2013.01); A61M 1/604 (2021.05); A61M 1/80 (2021.05); B30B 9/04 (2013.01); B30B 9/06 (2013.01); B30B 15/08 (2013.01); B30B 15/22 (2013.01); A61M 1/892 (2021.05); A61M 2202/08 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method for mechanically removing a fat phase from at least one adipose tissue and preparing adipose derived mesenchymal stem cells, the method comprising:
pressing the at least one adipose tissue within a gap between a first pressing element and a second pressing element and forcing out at least part of the fat phase from the at least one adipose tissue when the gap is reduced in size; and
maintaining the gap between the first pressing element and the second pressing element during pressing of the at least one adipose tissue by a distance controlling element so as to avoid over-pressing or crushing of the at least one adipose tissue and prevent damage to the adipose derived mesenchymal cells,
wherein the size of the gap is controlled to be correlated to a size of the at least one adipose tissue pressed between the first pressing element and the second pressing element, and wherein the gap has a size of less than 500 μm.