US 11,813,053 B2
Method and system for predicting patient recovery time from neuromuscular block
Helena Liisa Anneli Batsman, Espoo (FI); Kimmo Henrik Uutela, Helsinki (FI); and Markku Erik Spoof, Tuusula (FI)
Assigned to GE Precision Healthcare LLC, Wauwatosa, WI (US)
Filed by GE Precision Healthcare LLC, Wauwatosa, WI (US)
Filed on Aug. 9, 2019, as Appl. No. 16/536,553.
Prior Publication US 2021/0038120 A1, Feb. 11, 2021
Int. Cl. A61B 5/11 (2006.01); A61B 5/00 (2006.01)
CPC A61B 5/1106 (2013.01) [A61B 5/7275 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method to estimate recovery time of a patient from neuromuscular block (NMB), comprising:
applying a first series of stimulations to a nerve of the patient at a first measurement time;
measuring a plurality of muscle twitches in response to each of the first series of stimulations;
calculating a muscle response ratio based on the measured muscle twitches in response to the first series of stimulations;
utilizing a recovery model and the calculated muscle response ratio from the patient to generate a predicted recovery trend for the patient;
monitoring subsequent trend values measured from the patient based on muscle twitches measured in response to subsequent series of stimulations applied to the patient;
comparing the subsequent measured trend values to the predicted recovery trend; and
selectively modifying the predicted recovery trend based on the comparison,
wherein the estimation method is restarted when a measured trend value, from among the monitored subsequent trend values, at a measurement time is below the predicted recovery trend by more than a predetermined limit.