	US 7,449,451 B2
	Use of multiple antioxidant micronutrients as systemic biological radioprotective agents against potential ionizing radiation risks
Kedar N. Prasad, Denver, Colo. (US); Gerald M. Haase, Greenwood Village, Colo. (US); and William C. Cole, Centennial, Colo. (US)
Assigned to Premier Micronutrient Corporation, Nashville, Tenn. (US)
Filed on Aug. 28, 2002, as Appl. No. 10/229,274.
Prior Publication US 2003/0064955 A1, Apr. 03, 2003
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/714 (2006.01); A61K 31/59 (2006.01); A61K 31/555 (2006.01); A61K 31/525 (2006.01); A61K 31/51 (2006.01); A61K 31/4184 (2006.01); A61K 31/015 (2006.01)

U.S. Cl. 514—52 [514/251; 514/184; 514/393; 514/350; 514/167; 514/474; 514/458; 514/440; 514/552; 514/276; 514/562; 514/494; 514/574; 514/763]

7 Claims

1. A formulation consisting essentially of:


	Vitamin A (palmitate)	5,000 I.U.
	Beta-carotene (from natural D. salina)	15 mg
	Vitamin D-3 (cholecalciferol)	400 I.U.
	Natural soucre Vitamin E
	(d-alpha tocopherol)	100 I.U.
	(d-alpha tocopheryl acid succinate)	100 I.U.
	Buffered Vitamin C (calcium ascorbate)	500 mg
	Thiamine mononitrate	4 mg
	Riboflavin	5 mg
	Niacinamide ascorbate	30 mg
	d-calcium pantothenate	10 mg
	Pyridoxine hydrochloride	5 mg
	Cyanocobalamin	10 μg
	Folic Acid (Folacin)	800 μg
	D-Biotin	200 μg
	Selenium (1-seleno-methionine)	100 μg
	Chromium picolinate	50 μg
	Zinc glycinate	15 mg
	Calcium citrate	250 mg
	Magnesium citrate	125 mg

and a booster formulation selected from a group consisting essentially of 1000 mg of vitamin C, 400 international units of d-alpha tocopheryl acid succinate, 200 international units of alpha tocopherol, 500 mg of N-acetyl cysteine, 50 mg of beta-carotene, and 100 mg of alpha lipoic acid, wherein said formulation is designed to reduce the risk in humans exposed to ionizing radiation of becoming subjected to at least one condition selected from the group consisting essentially of radiation-induced acute leukemia, breast cancer, and thyroid cancer.