US 11,808,569 B2
Waveguide enhanced analyte detection apparatus
Daniel Carothers, Lucas, TX (US)
Assigned to Strike Photonics, Inc., Allen, TX (US)
Filed by STRIKE PHTONICS, INC, Dallas, TX (US)
Filed on Mar. 17, 2021, as Appl. No. 17/204,276.
Claims priority of provisional application 63/056,580, filed on Jul. 25, 2020.
Claims priority of provisional application 62/993,033, filed on Mar. 22, 2020.
Prior Publication US 2021/0293525 A1, Sep. 23, 2021
Int. Cl. B01L 3/00 (2006.01); G01N 21/65 (2006.01); G02B 6/12 (2006.01); B82Y 15/00 (2011.01); G01B 9/02056 (2022.01)
CPC G01B 9/02058 (2013.01) [B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); B82Y 15/00 (2013.01); G01N 21/65 (2013.01); G02B 6/12 (2013.01); B01L 2300/168 (2013.01); G02B 2006/12138 (2013.01); G02B 2006/12159 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A test strip, comprising:
an integrated photonic chip, comprising, an optical waveguide located on a photonic circuit substrate, a photonic circuit, comprising a laser optically coupled to the optical waveguide to input light into the waveguide, an interferometer optically coupled to the optical waveguide for receiving the light from the waveguide, and a photodetector positioned with respect to the interferometer to receive the light from the interferometer;
a microfluidic channel located in a silicon substrate and attached to the photonic circuit substrate and positioned over the optical waveguide, such that side surfaces and an outermost surface of the optical waveguide extend into the microfluidic channel, and wherein the microfluidic channel extends along a length of the optical waveguide, the microfluidic channel having a fluid input port and a fluid vent port located on opposing ends of the microfluidic channel, the microfluidic channel forming a fluid path between the fluid input port and the fluid vent port; and
nanoparticles located on or adjacent the optical waveguide within the microfluidic channel; and
a fluid collection strip, wherein the integrated photonic chip is located thereon adjacent an end of the fluid collection strip, the fluid collection strip having a fluid channel formed therein, the fluid collection strip having a first input port fluidly connected to the fluid channel and located adjacent an opposing end of the fluid collection strip for receiving a fluid into the fluid collection strip, and a second input port fluidly connected to the fluid channel and located adjacent the integrated photonic chip for allowing fluid to flow through the second input port and into the integrated photonic chip by way of a third fluid input port located on the integrated photonic chip and out of the integrated photonic chip by way of an exit port of the integrated photonic chip and a vent port fluidly connected to the the exit port of the integrated photonic chip.