CPC A61M 5/155 (2013.01) [A61K 38/13 (2013.01); A61K 38/21 (2013.01); A61K 38/26 (2013.01); A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61K 38/29 (2013.01); A61K 38/30 (2013.01); A61K 38/55 (2013.01); A61M 5/14244 (2013.01); A61M 31/002 (2013.01); A61K 9/4808 (2013.01); A61M 37/0069 (2013.01); A61M 2205/3331 (2013.01); A61M 2210/1042 (2013.01)] | 16 Claims |
1. An ingestible device suitable for swallowing into a lumen of a gastrointestinal tract of a patient, the lumen having a lumen wall, the device comprising:
a capsule sized to pass through the gastrointestinal tract;
a drug preparation;
a tissue penetrating member disposed in the capsule, the tissue penetrating member comprising the drug preparation; and
a delivery mechanism for advancing the tissue penetrating member from the capsule to the lumen wall, the delivery mechanism comprising:
an expandable member; and
a piston-cylinder assembly operably coupled to the expandable member and to the tissue penetrating member, wherein the piston-cylinder assembly comprises a piston slidably disposed in a cylinder, wherein the piston-cylinder assembly is at least partially disposed in the expandable member;
wherein the expandable member is configured to expand to cause the piston-cylinder assembly to apply a force against the tissue penetrating member and advance the drug preparation into the lumen wall.
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