CPC A61K 31/519 (2013.01) | 16 Claims |
1. A method of treating a subject with a central nerve system (CNS) disorder or neurodegenerative disorder, comprising administering an effective amount of a compound of formula (II):
R1 is selected from (C1-C8)alkyl, substituted (C1-C8)alkyl, (C2-C8)alkenyl, substituted (C2-C8)alkenyl, (C2-C8)alkynyl, substituted (C2-C8)alkynyl, (C1-C3)haloalkyl, (C1-C8)alkoxy, substituted (C1-C8)alkoxy, —CONH2, substituted amido, —NH2, substituted amino, —CO2H, cyano, halogen, hydroxyl, —NO2, —SO3H, —SO2NH2, substituted sulfonamide, and thiol;
R2 to R9 are independently selected from H, (C1-C8)alkyl, substituted (C1-C8)alkyl, (C2-C8)alkenyl, substituted (C2-C8)alkenyl, (C2-C8)alkynyl, substituted (C2-C8)alkynyl, (C1-C3)haloalkyl, (C1-C8)alkoxy, substituted (C1-C8)alkoxy, —CONH2, substituted amido, —NH2, substituted amino, —CO2H, cyano, halogen, hydroxyl, —NO2, —SO3H, —SO2NH2, substituted sulfonamide, and thiol,
or a solvate, a hydrate, a prodrug, and/or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof,
to the subject.
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