US 7,615,571 B2
Process for manufacture of pure (2S, 3aS, 7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl) butyl]amino]-1-oxopropyl] octahydro-1H-indole-2-carboxylic acid and its tert. butyl amine salt
Sanjay Tukaram Gunjal, Mumbai (India); Dilip Uttam Jadhav, Mumbai (India); Ashok Kumar, Mumbai (India); Mathur Arpana, Thane (India); Nalinakshya Balaram Panda, Thane (India); and Satish Rajanikant Soudagar, Mumbai (India)
Assigned to IPCA Laboratories Ltd., Mumbai (India)
Filed on Jan. 03, 2006, as Appl. No. 11/324,349.
Application 11/324349 is a continuation in part of application No. 11/140226, filed on May 27, 2005, abandoned.
Claims priority of application No. 17.MUM.2005 (IN), filed on Jan. 06, 2005.
Prior Publication US 2007/0021490 A1, Jan. 25, 2007
Int. Cl. A61K 31/403 (2006.01); C07D 209/12 (2006.01)
U.S. Cl. 514—412  [548/452] 15 Claims
 
1. A compound of general formula IVA,

OG Complex Work Unit Drawing
wherein R is an aryl alkyl group and wherein HA represents an acid capable of forming a salt.