US 7,612,208 B2
	Crystalline form of the salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or the solvate of the salt and a process for preparing the same
Tomohiro Matsushima, Tsukuba (Japan); Taiju Nakamura, Kamisu (Japan); Kazuhiro Yoshizawa, Kamisu (Japan); Atsushi Kamada, Tsukuba (Japan); Yusuke Ayata, Kamisu (Japan); Naoko Suzuki, Ushiku (Japan); Itaru Arimoto, Tokyo (Japan); Takahisa Sakaguchi, Tsukuba (Japan); and Masaharu Gotoda, Tsukuba (Japan)
Assigned to Eisai R&D Management Co., Ltd., Tokyo (Japan)
Appl. No. 10/577,531 PCT Filed Dec. 22, 2004, PCT No. PCT/JP2004/019223 § 371(c)(1), (2), (4) Date Apr. 28, 2006, PCT Pub. No. WO2005/063713, PCT Pub. Date Jul. 14, 2005.
Claims priority of application No. 2003-430939 (JP), filed on Dec. 25, 2003.
Prior Publication US 2007/0078159 A1, Apr. 05, 2007
Int. Cl. C07D 215/38 (2006.01)

U.S. Cl. 546—159  [546/153; 514/312]

28 Claims

1. A crystalline form (Form A) of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide methanesulfonate having diffraction peaks at diffraction angles (2θ±0.2°) of 9.65° and 18.37° in a powder X-ray diffraction.