US 7,612,071 B2
Compositions and methods employing aminopterin
Barton Aron Kamen, Princeton Junction, N.J. (US); Peter David Cole, Montclair, N.J. (US); Angela King Smith, West Windsor, N.J. (US); and John Anthony Zebala, Sammamish, Wash. (US)
Assigned to Syntrix Biosystems, Inc., Auburn, Wash. (US)
Filed on Mar. 09, 2005, as Appl. No. 11/78,614.
Claims priority of provisional application 60/552787, filed on Mar. 12, 2004.
Prior Publication US 2005/0209239 A1, Sep. 22, 2005
Int. Cl. A01N 43/54 (2006.01); A01N 43/60 (2006.01); A61K 31/4995 (2006.01); A61K 31/505 (2006.01)
U.S. Cl. 514—249 3 Claims
 
1. A method for treating a disorder in a patient, comprising administering to said patient a pharmaceutical composition comprising a therapeutically effective amount of aminopterin, or a pharmaceutically acceptable salt thereof, wherein the disorder is refractory acute lymphoblastic leukemia.