US 7,612,041 B2
Isolated activin-binding ActRIIa polypeptide comprising the SEQ ID NO: 7 and uses for promoting bone growth
John Knopf, Carlisle, Mass. (US); and Jasbir Seehra, Lexington, Mass. (US)
Assigned to Acceleron Pharma Inc., Cambridge, Mass. (US)
Filed on Nov. 22, 2006, as Appl. No. 11/603,485.
Claims priority of provisional application 60/739462, filed on Nov. 23, 2005.
Claims priority of provisional application 60/783322, filed on Mar. 17, 2006.
Claims priority of provisional application 60/844855, filed on Sep. 15, 2006.
Prior Publication US 2007/0249022 A1, Oct. 25, 2007
Int. Cl. A61K 38/00 (2006.01); C07K 16/46 (2006.01)
U.S. Cl. 514—12  [530/350] 30 Claims
 
1. An isolated activin-binding ActRIIa polypeptide comprising the amino acid sequence of SEQ ID NO:7.