US 7,612,030 B2
Enzymatic production of peracids using perhydrolytic enzymes
Robert DiCosimo, Chadds Ford, Pa. (US); Mark S. Payne, Wilmington, Del. (US); Vincent Brian Croud, Sheffield (United Kingdom); John E. Gavagan, Wilmington, Del. (US); Lorraine W. Wagner, Newark, Del. (US); and Eugenia Costa Hann, Carneys Point, N.J. (US)
Assigned to E. I. du Pont de Nemours and Company, Wilmington, Del. (US)
Filed on Apr. 28, 2006, as Appl. No. 11/413,246.
Claims priority of provisional application 60/676116, filed on Apr. 29, 2005.
Prior Publication US 2007/0105740 A1, May 10, 2007
Int. Cl. C11D 3/39 (2006.01); C11D 3/395 (2006.01); C11D 3/386 (2006.01); A01N 25/00 (2006.01)
U.S. Cl. 510—303  [422/28; 422/29; 424/94.2; 424/405; 435/129; 435/134; 435/135; 435/136; 435/264; 510/226; 510/300; 510/305; 510/306; 510/310; 510/375; 510/393] 32 Claims
 
1. A process for producing a concentrated aqueous peracid solution comprising;
a) providing a set of peracid reaction components, said components comprising:
1) at least one substrate selected from the group consisting of:
i) esters having the structure

OG Complex Work Unit Drawing
wherein R1=C1 to C10 straight chain or branched chain alkyl optionally substituted with an hydroxyl or a C1 to C4 alkoxy group and R2=C1 to C10 straight chain or branched chain alkyl group, (CH2CH2—O)nH or (CH2CH(CH3)—O)nH and n=1 to 10;
ii) glycerides having the structure

OG Complex Work Unit Drawing
wherein R1=C1 to C10 straight chain or branched chain alkyl optionally substituted with an hydroxyl or a C1 to C4 alkoxy group and R3 and R4 are individually H or R1C(O); and
iii) amides having the structure

OG Complex Work Unit Drawing
wherein R5 and R6are individually H, acetyl, or a C1 to C5 straight chain or branched alkyl group;
2) a source of peroxygen that provides a concentration of at least 500 mM hydrogen peroxide upon combining said reaction components; and
3) at least one enzyme catalyst having perhydrolase activity, wherein said enzyme catalyst is selected from the group consisting of lipases, esterases, proteases, and mixtures thereof; and
b) combining said reaction components at a pH of about 2.5 to about 7.5, whereby a concentrated peracid solution is produced within at least about 5 minutes to about 2 hours after combining said reaction components.