US 7,611,674 B2
Device for the carrying out of chemical or biological reactions
Wolfgang Heimberg, Ebersberg (Germany); Thomas Hermann, Ottobrunn (Germany); Matthias Knulle, Grafing (Germany); Markus Schurf, Siegsdorf (Germany); and Tilmann Wagner, Grafing (Germany)
Assigned to Applied Biosystems, LLC, Carlsbad, Calif. (US)
Filed on Jan. 11, 2007, as Appl. No. 11/651,985.
Application 11/651985 is a continuation of application No. 10/089136, previously published as PCT/EP00/09569, filed on Sep. 29, 2000.
Claims priority of application No. 299 17 313 (DE), filed on Oct. 01, 1999.
Prior Publication US 2007/0140926 A1, Jun. 21, 2007
Int. Cl. B01L 11/02 (2006.01)
U.S. Cl. 422—104  [422/109] 8 Claims
OG exemplary drawing
 
1. A thermocycler for processing biological or chemical samples, comprising:
a block comprising physically discrete segments, the segmented block configured to receive a plurality of sample volumes in a standard microtiter plate;
a thermoelectric device comprising a plurality of thermoelectric elements, each thermoelectric element in dedicated thermal communication with only one segment of the block such that each segment is aligned with a thermoelectric device; and
a plurality of temperature equalization plates, each temperature equalization plate being dedicated to provide a substantially uniform temperature to only one segment of the block during thermal cycling such that each segment is aligned with a respective temperature equalization plate, and each temperature equalization plate being configured to circulate a cooling medium therein.