US 7,608,678 B2
	Hydrolytically degradable polymers and hydrogels made therefrom
J. Milton Harris, Huntsville, Ala. (US); Michael D. Bentley, Huntsville, Ala. (US); Xuan Zhao, Dong Cheng District (China); and Xiaoming Shen, Madison, Ala. (US)
Assigned to Nektar Therapeutics, San Carlos, Calif. (US)
Filed on Aug. 03, 2007, as Appl. No. 11/890,162.
Application 11/890162 is a continuation of application No. 11/377973, filed on Mar. 17, 2006, granted, now 7,259,224.
Application 11/377973 is a continuation of application No. 10/412642, filed on Apr. 10, 2003, granted, now 7,074,878.
Application 10/412642 is a continuation of application No. 10/076018, filed on Feb. 14, 2002, abandoned.
Application 10/076018 is a continuation of application No. 09/459312, filed on Dec. 10, 1999, granted, now 6,348,558.
Prior Publication US 2007/0276116 A1, Nov. 29, 2007
Int. Cl. C08G 64/00 (2006.01); C08G 63/02 (2006.01)

U.S. Cl. 528—196  [424/78.27; 424/78.32; 424/94.63; 525/326.7; 525/329.9; 526/286; 528/198]

3 Claims

1. A water soluble polymer comprising multiple hydrolytically degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an oligomer linked thereto by the carbonate linkage, wherein the oligomer is branched and, prior to being linked by the carbonate linkage, has the formula: R3[O—(—CHR1CH2—O—)n—]mH where R3 is a core branching moiety, R1 is H, (n) can range from 2 to 2000, and m is at least 3.