| US 7,608,268 B2 | ||
| Ferritin fusion proteins for use in vaccines and other applications | ||
| Daniel C. Carter, Huntsville, Ala. (US); and Chester Q. Li, Madison, Ala. (US) | ||
| Assigned to New Century Pharmaceuticals, Inc., Huntsville, Ala. (US) | ||
| Filed on Mar. 14, 2006, as Appl. No. 11/374,066. | ||
| Application 11/374066 is a continuation of application No. 10/435666, filed on May 12, 2003, granted, now 7,097,841. | ||
| Claims priority of provisional application 60/379145, filed on May 10, 2002. | ||
| Prior Publication US 2006/0251679 A1, Nov. 09, 2006 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. A61K 39/12 (2006.01); A61K 39/395 (2006.01); C07K 19/00 (2006.01); C12N 15/62 (2006.01) | ||
| U.S. Cl. 424—192.1 [424/185.1; 424/186.1; 424/188.1; 424/221.1; 424/178.1; 424/134.4; 530/350; 530/400; 530/387.3; 514/2; 514/6; 536/23.4; 435/262] | 19 Claims |
| 1. A ferritin fusion protein comprising a fusion protein selected from the group consisting of an L-chain ferritin protein
fused at the C terminus with a protein or peptide capable of being fused to ferritin without interfering with the polymeric
assembly of the resulting fusion protein and an L-chain ferritin protein fused at the N terminus with a protein or peptide
capable of being fused to ferritin without interfering with the polymeric assembly of the resulting fusion protein,
wherein the protein is connected to ferritin by means of a spacer comprising at least one amino acid.
|