| US 7,432,251 B2 | ||
| Methods of treating neurological diseases by regulating migration of neuroblasts in the adult nervous system with tenascin-R | ||
| Armen Saghatelyan, Gif-sur-Yvette (France); Antoine de Chevigny, Paris (France); and Pierre-Marie Lledo, Antony (France) | ||
| Assigned to Institut Pasteur, Paris (France) | ||
| Filed on Mar. 14, 2005, as Appl. No. 11/78,479. | ||
| Prior Publication US 2006/0205644 A1, Sep. 14, 2006 | ||
| Int. Cl. A61K 31/00 (2006.01) | ||
| U.S. Cl. 514—44 [514/2; 530/350] | 29 Claims |
| 1. A method for directing migration of neuroblasts in a part of the central nervous system (CNS) or peripheral nervous system
(PNS) of a mammal, wherein the method comprises:
administering to the CNS or PNS of a mammal a composition comprising tenascin-R (TNR) in an amount sufficient to direct migration
of the neuroblasts within the CNS or within the PNS of said mammal.
|