US 7,598,240 B2
Benzothiazin-3-one compound and intermediate therefor
Fumio Samizo, Tokyo (Japan); Yoshihiro Horiuchi, Tokyo (Japan); Nobuhisa Fukuda, Osaka (Japan); Katsunori Tsuboi, Osaka (Japan); and Atsushi Makita, Oita (Japan)
Assigned to Dainippon Sumitomo Pharma Co., Ltd., Osaka (Japan)
Appl. No. 10/598,516
PCT Filed Feb. 28, 2005, PCT No. PCT/JP2005/003821
§ 371(c)(1), (2), (4) Date Jun. 18, 2007,
PCT Pub. No. WO2005/082872, PCT Pub. Date Sep. 09, 2005.
Claims priority of application No. 2004-057808 (JP), filed on Mar. 02, 2004.
Prior Publication US 2008/0058321 A1, Mar. 06, 2008
Int. Cl. C07D 279/16 (2006.01); A61K 31/5415 (2006.01)
U.S. Cl. 514—224.2  [544/49] 8 Claims
 
1. A benzothiazin-3-one compound represented by the formula (1):

OG Complex Work Unit Drawing
wherein n is 3 or 4; R is an ethyl group or a hydrogen atom; and R1 is a halogen atom, an alkoxy group, a haloalkyl group or a haloalkoxy group, or a pharmaceutically acceptable salt thereof.