US 7,595,426 B2
Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives
Michael Rack, Heidelberg (Germany); Sebastian Peer Smidt, Mannheim (Germany); Manuel Budich, Böhl-Iggelheim (Germany); Volker Maywald, Ludwigshafen (Germany); Michael Keil, Freinsheim (Germany); and Bernd Wolf, Fuβgönheim (Germany)
Assigned to BASF Aktiengesellschaft, Ludwigshafen (Germany)
Appl. No. 11/911,971
PCT Filed Apr. 21, 2006, PCT No. PCT/EP2006/061766
§ 371(c)(1), (2), (4) Date Oct. 19, 2007,
PCT Pub. No. WO2006/111583, PCT Pub. Date Oct. 26, 2006.
Claims priority of application No. 10 2005 018 934 (DE), filed on Apr. 22, 2005.
Prior Publication US 2008/0214878 A1, Sep. 04, 2008
Int. Cl. C07C 22/00 (2006.01); C07C 17/00 (2006.01)
U.S. Cl. 570—147  [570/155; 570/156] 18 Claims
 
1. A process for preparing 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene, which comprises the steps A) and B):
A) Chlorination of fluorobenzene of the formula II,

OG Complex Work Unit Drawing
 where X is fluorine or hydrogen, Z is nitro, bromine or chlorine and n is zero or 1-4, and
B) fluorination of the reaction products from step A) and isolation of the resulting 1,3,5-trifluoro-2,4,6-trichlorobenzene by distillation.