| US 7,592,452 B2 | ||
| Process for catalytically preparing aromatic or heteroaromatic nitriles | ||
| Nikolaus Müller, Monheim (Germany); Wolfgang Mägerlein, Mannheim (Germany); Matthias Beller, Ostseebad Nienhagen (Germany); Thomas Schareina, Cammin (Germany); and Alexander Zapf, Rosenheim (Germany) | ||
| Assigned to SaltigoGmbH, Langenfeld (Germany) | ||
| Filed on Aug. 27, 2007, as Appl. No. 11/895,728. | ||
| Claims priority of application No. 10 2006 042 439 (DE), filed on Sep. 09, 2006. | ||
| Prior Publication US 2009/0062541 A1, Mar. 05, 2009 | ||
| Int. Cl. C07D 239/24 (2006.01) | ||
| U.S. Cl. 544—242 [558/343; 546/286; 248/146; 248/214; 549/474] | 9 Claims |
| 1. Process for catalytically preparing optionally substituted aromatic or heteroaromatic nitriles of the general formula (I)
Ar—CN (I) by reacting the corresponding aryl halides of the general formula (II)
Ar—X (II) in which X is chlorine, bromine, or iodine and Ar is an optionally substituted aromatic or heteroaromatic radical,
wherein the reaction is performed in the presence of copper compounds, 1-alkylimidazoles, and a cyanide donor wherein the
cyanide donor is potassium hexacyanoferrate(II) or potassium hexacyanoferrate(III).
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