US 7,592,011 B2
Genes and proteins, and their use
Martin John Glenton Hughes, Berkshire (United Kingdom); Joseph David Santangelo, Berkshire (United Kingdom); Jonathan Douglas Lane, Berkshire (United Kingdom); Robert Feldman, Berkshire (United Kingdom); Joanne Christine Moore, Berkshire (United Kingdom); Richard James Dobson, Berkshire (United Kingdom); Paul Everest, Dumbartonshire (United Kingdom); Gordon Dougan, London (United Kingdom); and Rebecca Kerry Wilson, London (United Kingdom)
Assigned to Emergent Product Development UK Limited, Wokingham Berkshire (United Kingdom)
Filed on Sep. 17, 2004, as Appl. No. 10/944,521.
Application 10/944521 is a continuation of application No. 10/096162, filed on Mar. 11, 2002, granted, now 6,890,539, filed on May 10, 2005.
Application 10/096162 is a continuation in part of application No. 09/868352, granted, now 6,812,021, filed on Nov. 02, 2004, previously published as PCT/GB99/04377, filed on Dec. 22, 1999.
Claims priority of application No. 9828345.0 (GB), filed on Dec. 22, 1998; application No. 9828349.2 (GB), filed on Dec. 22, 1998; application No. 9828350.0 (GB), filed on Dec. 22, 1998; application No. 9828352.6 (GB), filed on Dec. 22, 1998; application No. 9828353.4 (GB), filed on Dec. 22, 1998; application No. 9828354.2 (GB), filed on Dec. 22, 1998; application No. 9828355.9 (GB), filed on Dec. 22, 1998; application No. 9828356.7 (GB), filed on Dec. 22, 1998; application No. 9828357.5 (GB), filed on Dec. 22, 1998; application No. 9828359.1 (GB), filed on Dec. 22, 1998; application No. 9900082.0 (GB), filed on Jan. 04, 1999; application No. 9900083.8 (GB), filed on Jan. 04, 1999; application No. 9900084.6 (GB), filed on Jan. 04, 1999; application No. 9900085.3 (GB), filed on Jan. 04, 1999; application No. 9900086.1 (GB), filed on Jan. 04, 1999; application No. 9901916.8 (GB), filed on Jan. 28, 1999; application No. 9901922.6 (GB), filed on Jan. 28, 1999; and application No. 0105922.9 (GB), filed on Mar. 09, 2001.
Prior Publication US 2005/0131210 A1, Jun. 16, 2005
Int. Cl. A61K 39/09 (2006.01); C07H 21/04 (2006.01); C12P 21/04 (2006.01); C12N 1/20 (2006.01)
U.S. Cl. 424—190.1  [424/184.1; 424/244.1; 536/23.7; 536/24.32; 530/300; 530/350; 435/69.1; 435/69.7; 435/252.3] 16 Claims
 
1. A method of inducing an immune response against Group B Streptococcus comprising administering to a subject a composition comprising an isolated polypeptide, which comprises an amino acid sequence at least 95% identical to SEQ ID NO: 2, wherein said polypeptide is recognized by an antibody that specifically binds to a polypeptide consisting of SEQ ID NO: 2.