US 7,591,860 B2
N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof
Stéphane Sabelle, Paris (France); Christian Blaise, Saint Mande (France); Philippe Breton, Noisy le Roi (France); and Jean-Jacques Vandenbossche, Begaar (France)
Assigned to L'Oreal, S.A., Paris (France)
Filed on Feb. 28, 2005, as Appl. No. 11/66,462.
Claims priority of provisional application 60/569630, filed on May 11, 2004.
Claims priority of application No. 04 02020 (FR), filed on Feb. 27, 2004.
Prior Publication US 2006/0026777 A1, Feb. 09, 2006
Int. Cl. A61K 8/00 (2006.01)
U.S. Cl. 8—405  [8/401; 8/406; 8/408; 8/421; 8/409] 18 Claims
 
1. A secondary para-phenylene diamine chosen from compounds of formula (I) and the addition salts thereof:

OG Complex Work Unit Drawing
wherein:
R is chosen from linear and branched C2-C18 alkyl radicals comprising from 2 to 4 hydroxyl groups, wherein the alkyl radicals are unsubstituted or substituted with at least one entity chosen from amino, mono(C1-C15)alkylamino, di(C1-C15)alkylamino, (C1-C15)alkylcarbonyl, amido, mono(C1-C15)alkylaminocarbonyl, and di(C1-C15)alkylaminocarbonyl groups, and wherein the alkyl radicals are interrupted with at least one heteroatom chosen from oxygen and nitrogen;
R1 is chosen from hydrogen, C1-C5 alkyl radicals, C1-C15 alkoxy radicals, hydroxy((C1-C15)alkoxy) radicals, (C1-C15)alkoxy(C1-C15)alkyl radicals, C1-C15 monohydroxyalkyl radicals, C1-C15 polyhydroxyalkyl radicals, and halogen atoms; and
n is an integer ranging from 1 to 4;
with the proviso that the compound of formula (I) is not N-(2,3-dihydroxypropyl)-para-phenylenediamine.