US 7,591,844 B2
Medical devices, drug coatings and methods for maintaining the drug coatings thereon
Gerard H. Llanos, Stewartsville, N.J. (US); Mark B. Roller, North Brunswick, N.J. (US); Angelo George Scopelianos, White House Station, N.J. (US); and Robert Falotico, Belle Mead, N.J. (US)
Assigned to Cordis Corporation, Miami Lakes, Fla. (US); and Wyeth, Madison, N.J. (US)
Filed on Nov. 16, 2007, as Appl. No. 11/941,351.
Application 11/941351 is a continuation of application No. 11/782770, filed on Jul. 25, 2007, abandoned.
Application 11/782770 is a continuation of application No. 11/437572, filed on May 19, 2006.
Application 11/437572 is a continuation of application No. 10/636435, filed on Aug. 07, 2003, granted, now 7,056,550.
Application 10/636435 is a continuation of application No. 09/962496, filed on Sep. 25, 2001, abandoned.
Application 09/962496 is a continuation in part of application No. 09/675882, filed on Sep. 29, 2000, abandoned.
Prior Publication US 2008/0051865 A1, Feb. 28, 2008
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/06 (2006.01); B32B 27/00 (2006.01); A61L 33/00 (2006.01)
U.S. Cl. 623—1.12  [623/1.43; 623/1.46; 623/1.49; 428/421; 427/2.25] 24 Claims
 
1. A device for intraluminal implantation in a vessel comprising a balloon-expandable stent and a pharmaceutical agent-containing coating, said coating comprising a biocompatible polyfluoro copolymer that comprises about eighty-five weight percent vinylidinefluoride copolymerized with about fifteen weight percent hexafluoropropylene and at least one pharmaceutical agent intermixed with said copolymer, wherein said coating has not been subjected to a maximum temperature greater than 60° C. during the coating process or afterward, thereby providing an adherent coating that remains adhered to the device upon expansion of the balloon-expandable stent.