US 11,754,554 B2
Systems and methods of fluidic sample processing
Shaunak Roy, San Mateo, CA (US); Melissa Takahashi, Cambridge, MA (US); Ian Gibbons, Newark, CA (US); Edmond Ku, Sunnyvale, CA (US); Thanh Dang, San Jose, CA (US); Tammy Burd, San Jose, CA (US); Adam Vollmer, San Francisco, CA (US); and Elizabeth A. Holmes, Palo Alto, CA (US)
Assigned to Labrador Diagnostics LLC, Wilmington, DE (US)
Filed by Labrador Diagnostics LLC, Wilmington, DE (US)
Filed on Jan. 11, 2017, as Appl. No. 15/403,553.
Application 15/403,553 is a continuation of application No. 14/534,064, filed on Nov. 5, 2014, granted, now 9,575,058.
Application 14/534,064 is a continuation of application No. 13/436,568, filed on Mar. 30, 2012, granted, now 8,883,518, issued on Nov. 11, 2014.
Application 13/436,568 is a continuation of application No. 12/221,816, filed on Aug. 6, 2008, granted, now 8,158,430, issued on Apr. 17, 2012.
Claims priority of provisional application 60/954,301, filed on Aug. 6, 2007.
Prior Publication US 2017/0192022 A1, Jul. 6, 2017
Int. Cl. G01N 33/53 (2006.01); G01N 35/10 (2006.01); G01N 33/49 (2006.01); G01N 27/07 (2006.01); G01N 33/86 (2006.01); G01N 27/06 (2006.01)
CPC G01N 33/5304 (2013.01) [G01N 27/07 (2013.01); G01N 33/49 (2013.01); G01N 33/5302 (2013.01); G01N 33/86 (2013.01); G01N 35/1002 (2013.01); G01N 27/06 (2013.01); G01N 2201/12746 (2013.01); G01N 2800/52 (2013.01); Y10S 435/973 (2013.01); Y10S 436/809 (2013.01); Y10T 436/106664 (2015.01)] 18 Claims
OG exemplary drawing
 
1. A system, comprising:
a sample processing device, comprising:
at least a first reagent reservoir and a second reagent reservoir;
a manifold connecting to the first and second reagent reservoirs; and
a calibration unit;
a cartridge comprising an assay assembly having a reaction site; and
a removable sample collection unit,
wherein the manifold fluidically routes a first reagent and a second reagent from the first reagent reservoir and the second reagent reservoir, respectively, to the cartridge, and
wherein the calibration unit comprises electrodes and is configured to provide a conductivity calibration measurement of a sample such that the calibration measurement is configured to calibrate a detectable signal from the assay assembly.