US 11,752,263 B2
Mixing and/or reconstitution system
Michael Schabbach, Frankfurt am Main (DE); Charlotte Emma Harvey, Harston (GB); Congyi Huang, Cambridge (GB); Timothy Charles Frearson, Harston (GB); Alexander David Norman, Harston (GB); Andrew Robert Potter, Harston (GB); and Gary Stacey, Harston (GB)
Assigned to Sanofi, Paris (FR)
Appl. No. 16/763,679
Filed by SANOFI, Paris (FR)
PCT Filed Nov. 15, 2018, PCT No. PCT/EP2018/081369
§ 371(c)(1), (2) Date May 13, 2020,
PCT Pub. No. WO2019/096904, PCT Pub. Date May 23, 2019.
Claims priority of application No. 17306597 (EP), filed on Nov. 17, 2017.
Prior Publication US 2020/0368433 A1, Nov. 26, 2020
Int. Cl. A61M 5/20 (2006.01); A61M 5/19 (2006.01); A61M 5/24 (2006.01); A61M 5/315 (2006.01); A61M 5/34 (2006.01)
CPC A61M 5/20 (2013.01) [A61M 5/19 (2013.01); A61M 5/24 (2013.01); A61M 5/31576 (2013.01); A61M 5/34 (2013.01); A61M 2205/19 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A base station that is part of a mixing and/or reconstitution system that comprises the base station, a device, a vial, a needle, and a sleeve-like supporting unit, wherein the device contains a first material within a first chamber and comprises a device housing and a plunger, wherein the vial contains a second material within a second chamber, wherein at least one of the first material and the second material is a fluid, wherein a self-supporting assembly is formed by the sleeve-like supporting unit and further comprises the device, the vial, and the needle, wherein the sleeve-like supporting unit is adapted to fix the device and the vial at pre-defined relative positions, wherein the needle is attached to the device and fluidly connected with the first chamber of the device, the base station comprising:
at least one drive unit;
a first slide;
a driver;
a housing; and
an unlocking feature,
wherein the base station is configured such that the self-supporting assembly, is attachable to the base station such that the device, the vial, and the needle are attachable to the base station in an initial position, in which
the device and the vial have a pre-defined distance between each other,
wherein in the initial position the at least one drive unit is connected to the first slide that moves the vial and/or the device housing relative to each other in an axial direction of the device into an activated position, wherein in the activated position:
the needle is fluidly connected with the second chamber, and
the at least one drive unit is connected to the driver that moves the plunger in the axial direction of the device such that during a fluid connection of the needle with the second chamber the first material is expelled from the first chamber of the device into the second chamber of the vial, or the second material is expelled from the second chamber of the vial into the first chamber of the device, or both the first material is expelled into the second chamber and the second material is expelled into the first chamber,
wherein an upper side of the housing of the base station has a recess that is adapted to receive and releasably fix the self-supporting assembly when the device and the vial are locked within the sleeve-like supporting unit, and
wherein the unlocking feature is configured to unlock parts of the sleeve-like supporting unit, allowing the device housing and the vial to move relative to each other when the self-supporting assembly is received and releasably fixed by the recess of the housing of the base station, wherein the sleeve-like supporting unit is positioned within the recess of the base station.