US 11,752,213 B2
Surfaces having reduced non-specific binding and antigenicity
Angus Hucknall, Durham, NC (US); Ashutosh Chilkoti, Durham, NC (US); Daniel Joh, Durham, NC (US); Nancy J. Ganson, Durham, NC (US); Yizhi Qi, Durham, NC (US); and Michael S. Hershfield, Durham, NC (US)
Assigned to Duke University, Durham, NC (US)
Filed by Duke University, Durham, NC (US)
Filed on Sep. 9, 2020, as Appl. No. 17/15,315.
Application 17/015,315 is a continuation in part of application No. 16/064,424, abandoned, previously published as PCT/US2016/068141, filed on Dec. 21, 2016.
Claims priority of provisional application 62/899,353, filed on Sep. 12, 2019.
Claims priority of provisional application 62/270,401, filed on Dec. 21, 2015.
Claims priority of provisional application 62/310,534, filed on Mar. 18, 2016.
Claims priority of provisional application 62/329,800, filed on Apr. 29, 2016.
Claims priority of provisional application 62/407,403, filed on Oct. 12, 2016.
Prior Publication US 2021/0046188 A1, Feb. 18, 2021
Int. Cl. A61K 47/58 (2017.01); A61K 47/59 (2017.01); C08L 71/08 (2006.01); A61K 47/64 (2017.01)
CPC A61K 47/58 (2017.08) [A61K 47/59 (2017.08); A61K 47/641 (2017.08); C08L 71/08 (2013.01); C08L 2203/02 (2013.01)] 40 Claims
 
1. A surface having reduced antigenicity and non-specific binding comprising: a surface comprising a plurality of poly[oligo(ethylene glycol) methyl ether methacrylate] (POEGMA) polymers comprising a poly(methyl methacrylate) backbone and a plurality of side chains covalently attached to the backbone, each side chain comprising 1 to 9 ethylene glycol monomers repeated in tandem and terminating with an alkoxy-moiety.