CPC A61K 39/001169 (2018.08) [A61K 39/39 (2013.01); C07H 15/24 (2013.01); A61K 2039/55577 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6081 (2013.01)] | 5 Claims |
1. A saponin mixture comprising:
(i) 1 to 15 mole % of a 1857 compound mixture, wherein the 1857 compound mixture comprises each of the following isolated compound of formula (I):
(a) wherein R1 is β-D-Apiose, R2 is
and R3 is H the 1857 compound V1A;
(b) wherein R1 is β-D-Apiose, R2 is H, and R3 is
the 1857 compound V1B;
(c) wherein R1 is β-D-Xylose, R2 is
and R3 is H, the 1857 compound V2A; and
(d) wherein R1 is β-D-Xylose, R2 is H, and R3 is
the 1857 compound V2B; and
(ii) 85 to 99 mole % of a 1989 compound mixture, wherein the 1989 compound mixture comprises each of the following isolated compound of formula (I):
(a) wherein R1 is β-D-Apiose, R2 is
and R3 is H, the 1989 compound V1B;
(b) wherein R1 is β-D-Apiose, R2 is H, and R3 is
the 1989 compound V2A;
(c) wherein R1 is β-D-Xylose, R2 is
and R3 is H, the 1989 compound V2B; and
(d) wherein R1 is β-D- Xylose, R2 is H, and R3 is
the 1989 compound V2B,
wherein the 1857 compound mixture comprises about 60-70 mole % of the 1857 compound V1A; 1-5 mole % of the 1857 compound V1B, about 30-40 mole % of the 1857 compound V2A, and 0.1-3 mole % of the 1857 compound V2B; and
wherein the 1989 compound mixture comprises about about 60-70 mole % of the 1989 compound V1A, 1-5 mole % of the 1989 compound V1B, about 30-40 mole % of the 1989 compound V2A, and 0.1-3 mole % of the 1989 compound V2B.
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