US 11,752,158 B2
Method of treating vitamin D insufficiency and deficiency
P. Martin Petkovich, Kingston (CA); Christian F. Helvig, Markham (CA); and Samir P. Tabash, Whitby (CA)
Assigned to EIRGEN PHARMA LTD., Waterford (IE)
Appl. No. 12/597,230
Filed by P. Martin Petkovich, Kingston (CA); Christian F. Helvig, Markham (CA); and Samir P. Tabash, Whitby (CA)
PCT Filed Apr. 25, 2008, PCT No. PCT/IB2008/003480
§ 371(c)(1), (2), (4) Date Dec. 24, 2009,
PCT Pub. No. WO2009/047644, PCT Pub. Date Apr. 16, 2009.
Claims priority of provisional application 60/913,849, filed on Apr. 25, 2007.
Prior Publication US 2010/0120728 A1, May 13, 2010
Int. Cl. A61K 31/592 (2006.01); A61K 31/593 (2006.01)
CPC A61K 31/592 (2013.01) [A61K 31/593 (2013.01)] 19 Claims
 
1. A method of maintaining or elevating serum levels of 25-hydroxyvitamin D, comprising co-administering to a subject 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2, wherein the weight or molar ratio of 25-hydroxyvitamin D3 to 25-hydroxyvitamin D2 is at least 1.5:1.