US 11,752,130 B2
Carboxylated psilocybin derivatives and methods of using
Jillian M. Hagel, Calgary (CA); Peter J. Facchini, Calgary (CA); and Chang-Chun Ling, Calgary (CA)
Assigned to Enveric Biosciences Canada Inc., Calgary (CA)
Filed by Enveric Biosciences Canada Inc., Calgary (CA)
Filed on Sep. 23, 2022, as Appl. No. 17/951,530.
Application 17/951,530 is a continuation of application No. PCT/CA2021/051712, filed on Dec. 1, 2021.
Claims priority of provisional application 63/248,037, filed on Sep. 24, 2021.
Claims priority of provisional application 63/119,786, filed on Dec. 1, 2020.
Prior Publication US 2023/0044066 A1, Feb. 9, 2023
Int. Cl. A61K 31/404 (2006.01); A61P 25/18 (2006.01); C07D 209/32 (2006.01); C07D 209/16 (2006.01); C07D 209/30 (2006.01)
CPC A61K 31/404 (2013.01) [A61P 25/18 (2018.01); C07D 209/16 (2013.01); C07D 209/30 (2013.01); C07D 209/32 (2013.01)] 17 Claims
 
1. A chemical compound having the formula (I):

OG Complex Work Unit Chemistry
wherein R7 is a carboxyl group and wherein R2 is a hydrogen atom, R5 or and R6 are a hydrogen atom, an alkyl group, or O-alkyl group, wherein R4 is an O-alkyl group, and wherein R3a and R3b are each independently a hydrogen atom, an alkyl group, acyl group or an aryl group.