	US 11,752,123 B2
	Compositions comprising theanine, s-adenosylmethionine (SAMe), and/or magnolia and phellodendron
Todd Henderson, Lancaster, SC (US); David Griffin, Forest Hill, MD (US); and David Bledsoe, Lancaster, SC (US)
Assigned to NUTRAMAX LABORATORIES, INC., Lancaster, SC (US)
Filed by NUTRAMAX LABORATORIES, INC., Lancaster, SC (US)
Filed on Jan. 25, 2021, as Appl. No. 17/157,139.
Application 17/157,139 is a continuation of application No. 16/437,701, filed on Jun. 11, 2019, granted, now 10,940,130.
Application 16/437,701 is a continuation of application No. 15/705,435, filed on Sep. 15, 2017, granted, now 10,335,384.
Application 15/705,435 is a continuation of application No. PCT/US2016/049630, filed on Aug. 31, 2016.
Claims priority of provisional application 62/212,080, filed on Aug. 31, 2015.
Prior Publication US 2021/0137870 A1, May 13, 2021
Int. Cl. A61K 31/198 (2006.01); A61K 36/756 (2006.01); A61K 38/01 (2006.01); A61K 45/06 (2006.01); A61K 31/7076 (2006.01); A61K 9/00 (2006.01); A61K 31/197 (2006.01); A61K 31/4045 (2006.01); A61K 36/575 (2006.01); A61K 38/38 (2006.01)

CPC A61K 31/198 (2013.01) [A61K 9/0053 (2013.01); A61K 31/197 (2013.01); A61K 31/4045 (2013.01); A61K 31/7076 (2013.01); A61K 36/575 (2013.01); A61K 36/756 (2013.01); A61K 38/018 (2013.01); A61K 38/38 (2013.01); A61K 45/06 (2013.01)]

10 Claims

1. An anxiolytic composition, comprising a synergistic combination of L-theanine and s-adenosylmethionine (SAMe) at a ratio of about 1.1:1, wherein the synergistic combination provides an anxiolytic change in a release pattern of one or more neurotransmitters.