US 7,590,273 B2
Estimation of solitary pulmonary nodule diameters with a hybrid segmentation approach
Toshiro Kubota, Malvern, Pa. (US); and Kazunori Okada, Plainsboro, N.J. (US)
Assigned to Siemens Corporate Research, Inc., Princeton, N.J. (US); and Siemens Medical Solutions USA, Inc., Malvern, Pa. (US)
Filed on Apr. 04, 2006, as Appl. No. 11/398,099.
Claims priority of provisional application 60/669438, filed on Apr. 08, 2005.
Prior Publication US 2006/0228013 A1, Oct. 12, 2006
Int. Cl. G06K 9/00 (2006.01)
U.S. Cl. 382—131  [382/128; 382/173; 382/224; 378/8; 378/62; 378/15; 378/901] 13 Claims
OG exemplary drawing
 
1. A computer-implemented method for estimating a diameter of an object of interest, comprising: a computer to implement the steps of:
providing a volume of interest comprising a marker identifying a location of the object of interest;
extracting a sub-volume of voxels around the marker; initializing at least two volumes of the sub-volume, wherein each of the voxels has at least two values corresponding to the at least two volumes, respectively;
performing, iteratively, a diffusion operation and a reaction operation on the voxels to update at least two values;
comparing, for each voxel, the at least two values to a threshold to assign each voxel to one of the at least two volumes, wherein the assignment of the voxels is a segmentation result;
performing a boundary check to determine whether the object of interest is solitary;
estimating a diameter of the object of interest from the segmentation result upon determining the object of interest to be solitary; and
extracting the object of interest by performing ellipsoid fit on the sub-volume and estimating a diameter of the object of interest upon determining the object of interest to be non-solitary.