| US 7,589,185 B2 | ||
| Nucleotide sequences and protein(s) encoded by such nucleotides for modulation of apoptosis | ||
| Rita Bisogni, Naples (Italy); Annalisa Lamberti, Naples (Italy); Antonello Petrella, Naples (Italy); Maria Fiammetta Romano, Naples (Italy); Maria Caterina Turco, Avellino (Italy); and Salvatore Venuta, Naples (Italy) | ||
| Assigned to Universita' degli Studi di Catanzaro “Magna Graecia”, Catanzaro (Italy) | ||
| Appl. No. 10/250,987 PCT Filed Jan. 10, 2002, PCT No. PCT/EP02/00171 § 371(c)(1), (2), (4) Date Nov. 25, 2003, PCT Pub. No. WO02/055553, PCT Pub. Date Jul. 18, 2002. |
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| Claims priority of application No. RM2001A0005 (IT), filed on Jan. 10, 2001. | ||
| Prior Publication US 2004/0072163 A1, Apr. 15, 2004 | ||
| Int. Cl. C07H 21/02 (2006.01) | ||
| U.S. Cl. 536—23.1 | 12 Claims |
| 1. An isolated Apoptosis-Induced and Regulator (AIR) polynucleotide selected from the group consisting of:
(a) a polynucleotide comprising full length SEQ ID NO: 1; and
(b) a fragment of SEQ ID NO: 1 selected from the group consisting of:
(i) a polynucleotide comprising full length SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, and SEQ ID NO:5, encoding full length SEQ
ID NO:12, SEQ ID NO:13, SEQ ID NO:14, and SEQ ID NO:15, respectively; and
(ii) a polynucleotide of at least 15 bases in length from SEQ ID NO: 4 or 5.
|