| US 7,588,916 B2 | ||
| T1R taste receptors and genes encoding same | ||
| Jon Elliott Adler, San Diego, Calif. (US); Xiaondong Li, San Diego, Calif. (US); Lena Staszewski, San Diego, Calif. (US); Shawn O'Connell, Encinitas, Calif. (US); and Sergey Zozulya, San Diego, Calif. (US) | ||
| Assigned to Senomyx, Inc., San Diego, Calif. (US) | ||
| Filed on May 08, 2007, as Appl. No. 11/745,857. | ||
| Application 11/745857 is a continuation of application No. 10/035045, filed on Jan. 03, 2002, granted, now 7,241,880. | ||
| Prior Publication US 2007/0292944 A1, Dec. 20, 2007 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. C12N 15/12 (2006.01); C07K 14/705 (2006.01) | ||
| U.S. Cl. 435—69.1 [435/252.3; 435/320.1; 536/23.5] | 10 Claims |
| 1. A vector containing an isolated nucleic acid which encodes a human hT1R2 taste receptor, wherein said hT1R2 encoding nucleic
acid is selected from the following:
(i) a nucleic acid which encodes the human T1R2 polypeptide in SEQ ID NO: 21;
(ii) a nucleic acid which encodes a polypeptide having at least 90% sequence identity to the human T1R2 polypeptide in SEQ
ID NO: 21;
(iii) a nucleic acid which hybridizes to the complement of the human T1R2 encoding nucleic acid sequence contained in SEQ
ID NO: 23 under stringent hybridization conditions which consist of hybridization in 50% formamide, 5×SSC and 1% SDS, incubating
at 42° C., with wash in 0.2×SSC and 0.1% SDS at 65° C., wherein said hybridization and wash steps are each carried out for
at least 1 minute; and
(iv) a nucleic acid encoding a human T1R2 polypeptide having the sequence in SEQ ID NO: 21.
|