US 7,588,780 B2
Embolization
Marcia Buiser, Watertown, Mass. (US); Marc Bellisario, Stoneham, Mass. (US); David Knapp, Shoreview, Minn. (US); Stephan Mangin, Ashland, Mass. (US); and Janel Lanphere, Newton, Mass. (US)
Assigned to Boston Scientific Scimed, Inc., Maple Grove, Minn. (US)
Filed on Aug. 09, 2002, as Appl. No. 10/215,594.
Application 10/215594 is a continuation in part of application No. 10/109966, filed on Mar. 29, 2002.
Prior Publication US 2003/0185896 A1, Oct. 02, 2003
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/14 (2006.01); A61K 9/50 (2006.01); B01J 13/02 (2006.01); B32B 15/02 (2006.01)
U.S. Cl. 424—501  [424/489; 264/4.1; 264/4.33; 264/4.7; 427/213.34; 428/402.21] 48 Claims
OG exemplary drawing
 
1. An embolic composition, comprising:
substantially spherical embolic particles having a diameter of about 1500 micron or less, the particles comprising polyvinyl alcohol, and including a first region including pores having a first predominant pore size and a second region surrounding the first region and including pores having a second predominant pore size,
wherein the first predominant pore size is larger than the second predominant pore size.