US 7,588,535 B2
Apparatus, method and system for intravascular photographic imaging
Doron Adler, Nesher (Israel); Alex Zaretski, Nesher (Israel); Ofer Pillar, Kirvat Haim (Israel); Keren Shafrir, Haifa (Israel); and Mordechai Segev, Ramat Alon (Israel)
Assigned to C2Cure Inc., Wilmington, Del. (US)
Appl. No. 10/498,150
PCT Filed Dec. 11, 2002, PCT No. PCT/IL02/00999
§ 371(c)(1), (2), (4) Date Feb. 25, 2005,
PCT Pub. No. WO03/053226, PCT Pub. Date Jul. 03, 2003.
Prior Publication US 2005/0165279 A1, Jul. 28, 2005
Int. Cl. A61B 1/04 (2006.01); A61B 6/00 (2006.01)
U.S. Cl. 600—109  [600/178; 600/181; 600/160; 600/476; 600/477] 58 Claims
OG exemplary drawing
 
38. An system for providing an image of a target region located within an intravascular environment, said system comprising an imaging apparatus comprising:
a. a camera having at least one light sensing region for detecting light; and
b. at least one light source for emitting light to impinge upon said target region, said light source being controllable to emit said light to impinge upon a predetermined field including said target region and substantially excluding surroundings of said target region, thereby to reduce an amount of reflected light generated by said surroundings from being detected by said light sensing region; and
the system further comprising a processor and stored instructions for reconstruction of at least one image from light detected by said light sensing region, said reconstruction being based upon expected light reflection behavior for light emitted within a pulse related radially expanding and contracting vascular vessel in order to recognize and exclude light that is not expected according to said behavior, wherein the stored instructions include a model of brightness variation behavior expected from a vascular wall given that the vascular wall moves in and out in accordance with a pulse.