US 7,585,844 B2
	Myosin light chain kinase inhibitors and methods of use
Jerrold R. Turner, Wilmette, Ill. (US); and Randall J. Mrsny, Los Altos Hills, Calif. (US)
Assigned to The University of Chicago, Chicago, Ill. (US); and University College Cardiff Consultants Ltd., Cardiff (United Kingdom)
Filed on Apr. 21, 2005, as Appl. No. 11/111,463.
Claims priority of provisional application 60/564313, filed on Apr. 21, 2004.
Prior Publication US 2005/0261196 A1, Nov. 24, 2005
Int. Cl. A61K 38/08 (2006.01)

U.S. Cl. 514—15  [530/328]

8 Claims

1. An inhibitor of myosin light chain kinase comprising SEQ ID NO: 13 and having at least one amino acid that is a D-amino acid, wherein the inhibitor having at least one D-amino acid retains at least substantially the same biological activity relative to the same inhibitor having all L-amino acids and wherein said inhibitor has an amino acid sequence of 9 to 120 amino acids.