US 7,585,509 B2
	Erb-2 receptor targeting peptide
Thomas P. Quinn, Columbia, Mo. (US); and Natalia G. Karasseva, Columbia, Mo. (US)
Assigned to The Curators of The University of Missouri, Columbia, Mo. (US)
Appl. No. 10/520,408 PCT Filed Jul. 03, 2003, PCT No. PCT/US03/21150 § 371(c)(1), (2), (4) Date May 17, 2005, PCT Pub. No. WO2004/005320, PCT Pub. Date Jan. 15, 2004.
Claims priority of provisional application 60/394174, filed on Jul. 03, 2002.
Prior Publication US 2005/0220706 A1, Oct. 06, 2005
Int. Cl. A61K 39/395 (2006.01); A61K 51/08 (2006.01); C07K 19/00 (2006.01); C07K 7/06 (2006.01); A61K 38/08 (2006.01)

U.S. Cl. 424—195.11  [424/184.1; 424/185.1; 424/192.1; 424/193.1; 424/1.11; 424/1.53; 424/1.57; 424/1.69; 514/2; 514/16; 530/329; 530/350; 530/402]

21 Claims

1. A method for targeting an agent to a cancer cell expressing ErbB-2 comprising bringing said cancer cell into contact with a peptide-agent complex, wherein said peptide comprises the sequence KCCYSL (SEQ ID NO:1) and said peptide binds to the extracellular domain of ErbB-2, wherein said agent is a diagnostic agent, a chemotherapeutic, a radiotherapeutic, a toxin or a cytokine.