US 7,585,501 B2
	Compositions and methods for treating kidney disease
Robb Krumlauf, Kansas City, Mo. (US); and Debra Ellies, Kansas City, Mo. (US)
Assigned to Stowers Institute for Medical Research, Kansas City, Mo. (US)
Filed on Dec. 20, 2006, as Appl. No. 11/613,658.
Application 11/613658 is a continuation in part of application No. 11/508701, filed on Aug. 23, 2006.
Application 11/508701 is a continuation in part of application No. 10/464368, filed on Jun. 16, 2003.
Claims priority of provisional application 60/710803, filed on Aug. 23, 2005.
Claims priority of provisional application 60/388970, filed on Jun. 14, 2002.
Prior Publication US 2007/0298038 A1, Dec. 27, 2007
Int. Cl. A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01)

U.S. Cl. 424—130.1  [424/141.1; 424/144.1; 530/387.1; 530/388.1; 530/388.2]

6 Claims

1. A method for treating nephronic degeneration comprising administering to a patient a composition comprising a therapeutically effective amount of an antibody that specifically binds a peptide selected from the group consisting of SEQ ID NOS: 15-18, and 217, wherein the antibody interferes with the interaction between SOST and a SOST binding partner selected from the group consisting of LRP5, LRP6, and BMP.