| US 7,585,412 B2 | ||
| Specialized hollow fiber membranes for plasmapheresis and ultrafiltration | ||
| Reynolds G. Gorsuch, Yountville, Calif. (US); Henry Grage, Alpharetta, Ga. (US); Harold H. Handley, Jr., Encinitas, Calif. (US); Harold W. Peters, Martinez, Calif. (US); and Jacob C. Kearns, Martinez, Calif. (US) | ||
| Assigned to Transvivo, Inc., Napa, Calif. (US) | ||
| Filed on Apr. 14, 2006, as Appl. No. 11/404,415. | ||
| Application 10/666185 is a division of application No. 09/549131, filed on Apr. 13, 2000, granted, now 6,802,820. | ||
| Application 11/404415 is a continuation in part of application No. 10/959918, filed on Oct. 06, 2004, granted, now 7,195,711. | ||
| Application 10/959918 is a continuation in part of application No. 10/666185, filed on Sep. 17, 2003, granted, now 6,802,971. | ||
| Prior Publication US 2007/0023353 A1, Feb. 01, 2007 | ||
| This patent is subject to a terminal disclaimer. | ||
| Int. Cl. B01D 69/06 (2006.01); B01D 71/66 (2006.01); B01D 63/02 (2006.01) | ||
| U.S. Cl. 210—500.23 [210/500.41; 604/6.04; 604/6.09; 604/27] | 30 Claims |
| 1. A plasmapheresis and/or ultrafiltration membrane comprising:
a plurality of elongated hollow fibers, having an outer wall, each fiber comprising a higher mass density outer wall zone
and an outer wall surface for being exposed to whole blood, wherein said higher mass density outer wall zone has a pore size
capable of separating plasma and plasma components from whole blood by passing plasma and plasma components therethrough,
and one or more lower mass density inner wall zones, an inner wall and an interior lumen extending along the length thereof,
and characterized by having an average elongation breaking force strength of at least about 0.2 lbs. and an average elongation
of at least about 45%, and wherein the fiber wall structure is a continuous change in mass density from said outer wall to
said inner wall and comprises a continuum of voids bounded by solid frames.
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