US 11,738,123 B2
Implant having controlled generation rate of reactive oxygen species and method of controlling generation of reactive oxygen species using the same
Myoung-Ryul Ok, Seoul (KR); Jimin Park, Seoul (KR); Yu Chan Kim, Seoul (KR); Hyun Kwang Seok, Seoul (KR); Hyung-Seop Han, Seoul (KR); Hojeong Jeon, Seoul (KR); Hyunseon Seo, Seoul (KR); Jee-Wook Lee, Seoul (KR); Jin Kyung Jeon, Seoul (KR); Gayoung Jung, Seoul (KR); Jong Woong Park, Seoul (KR); and Ji Hun Park, Seoul (KR)
Assigned to Korea Institute of Science and Technology, Seoul (KR); and Korea University Research and Business Foundation, Seoul (KR)
Filed by KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, Seoul (KR); and KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, Seoul (KR)
Filed on Jun. 3, 2020, as Appl. No. 16/891,195.
Claims priority of application No. 10-2019-0066915 (KR), filed on Jun. 5, 2019; and application No. 10-2019-0149796 (KR), filed on Nov. 20, 2019.
Prior Publication US 2020/0384165 A1, Dec. 10, 2020
Int. Cl. A61L 31/16 (2006.01); A61B 17/86 (2006.01); A61B 17/80 (2006.01); A61K 9/00 (2006.01); A61K 33/00 (2006.01); A61L 31/02 (2006.01); F16B 35/04 (2006.01); A61F 2/28 (2006.01); A61B 17/00 (2006.01); C25D 11/00 (2006.01)
CPC A61L 31/16 (2013.01) [A61B 17/80 (2013.01); A61B 17/8605 (2013.01); A61B 17/866 (2013.01); A61F 2/2846 (2013.01); A61K 9/0024 (2013.01); A61K 33/00 (2013.01); A61L 31/022 (2013.01); F16B 35/04 (2013.01); A61B 2017/00893 (2013.01); C25D 11/00 (2013.01)] 37 Claims
OG exemplary drawing
 
1. An implant having a controlled generation rate of reactive oxygen species, the implant comprising:
a body made of a metallic material and having a groove;
a first filling metal filling a region inside the groove; and
a second filling metal filling the groove on the first filling metal,
wherein the second filling metal has an ionization tendency different from that of the first filling metal, and
both the first filling metal and the second filling metal have ionization tendencies higher than that of the body.