US 11,737,459 B2
Use of nootkatone to kill sap-sucking insects
Jean Davin Amick, Lexington, KY (US); Bryan N. Julien, Lexington, KY (US); and Henrik Meyer, Dronningmolle (DK)
Assigned to EVOLVA SA, Reinach (CH)
Appl. No. 16/86,501
Filed by EVOLVA SA, Reinach (CH)
PCT Filed Mar. 24, 2017, PCT No. PCT/EP2017/057138
§ 371(c)(1), (2) Date Sep. 19, 2018,
PCT Pub. No. WO2017/162887, PCT Pub. Date Sep. 28, 2017.
Claims priority of provisional application 62/352,669, filed on Jun. 21, 2016.
Claims priority of provisional application 62/313,001, filed on Mar. 24, 2016.
Prior Publication US 2019/0069543 A1, Mar. 7, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A01N 35/06 (2006.01)
CPC A01N 35/06 (2013.01) 14 Claims
 
1. A method of treating a sap-sucking insect infestation or reducing the population of sap-sucking insects on a plant by applying a composition, wherein said treatment is associated with a reduced risk for skin irritation for a human or animal coming into contact with the composition, the method comprising:
applying an effective amount of a nootkatone-containing composition to a surface or area to be treated,
wherein the nootkatone is derived from oxidation of valencene that was produced by fermentation,
wherein the nootkatone is nootkatone ex valencene,
wherein the nootkatone ex valencene is limonene- and bergapten-free, and
wherein the applied nootkatone ex valencene-containing composition comprises about 0.1% to about 10% nootkatone ex valencene, and
wherein the nootkatone-containing composition has a reduced risk for causing skin irritation when applied topically compared to a nootkatone composition containing nootkatone that is neither limonene- nor bergapten-free.