| US 7,579,484 B2 | ||
| Method for the production of monoalkylamino ketones | ||
| Kai Fabian, Wilhelmsfeld (Germany); Claus-Peter Niesert, Seeheim-Jugenheim (Germany); Joachim Kralik, Darmstadt (Germany); and Karl-Heinz Glüsenkamp, Essen (Germany) | ||
| Assigned to Merck Patent GmbH, Darmstadt (Germany) | ||
| Appl. No. 10/525,820 PCT Filed Aug. 01, 2003, PCT No. PCT/EP03/08514 § 371(c)(1), (2), (4) Date Feb. 25, 2005, PCT Pub. No. WO2004/020391, PCT Pub. Date Mar. 11, 2004. |
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| Claims priority of application No. 102 40 026 (DE), filed on Aug. 27, 2002. | ||
| Prior Publication US 2006/0122405 A1, Jun. 08, 2006 | ||
| Int. Cl. C07D 333/06 (2006.01); C07D 333/26 (2006.01); C07D 307/36 (2006.01); C07D 307/46 (2006.01); C07D 307/56 (2006.01) | ||
| U.S. Cl. 549—72 [549/498] | 17 Claims |
1. A monoalkylaminoketone compound of the formula I
 in which
R1 denotes a thienyl or furyl radical which is unsubstituted or mono- or polysubstituted by R3 and/or R4, provided that R1 is not 3-thienyl substituted by both R3 and R4 where both R3 and R4 are methyl,
R2 denotes alkyl having 1-20 C atoms,
R3, R4 each, independently of one another, denote H, alkyl or alkoxy having 1-20 C atoms, aryl, aryloxy or COOR2, F, Br, OH, CN, NO2, N(R2)2 or NHCOR2,
or a salt thereof.
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