US 7,579,447 B2
	Antibodies against LLG polypeptides of the triacylglycerol lipase family
Michael C. Jaye, Glenside, Pa. (US); Kim-Anh Thi Doan, Audubon, Pa. (US); John A. Krawiec, Gulph Mills, Pa. (US); Kevin J. Lynch, Gurnee, Ill. (US); Dilip V. Amin, Lansdale, Pa. (US); and Victoria J. South, Collegeville, Pa. (US)
Assigned to Aventis Pharmaceuticals Inc., Bridgewater, N.J. (US)
Filed on Mar. 07, 2006, as Appl. No. 11/369,410.
Application 11/369410 is a division of application No. 10/128449, filed on Apr. 23, 2002, granted, now 7,056,720.
Application 10/128449 is a division of application No. 08/985492, filed on Dec. 05, 1997, granted, now 6,395,530.
Claims priority of provisional application 60/032254, filed on Dec. 06, 1996.
Claims priority of provisional application 60/032783, filed on Dec. 06, 1996.
Prior Publication US 2007/0101451 A1, May 03, 2007
Int. Cl. C07K 16/00 (2006.01); C07K 16/40 (2006.01); C12N 5/06 (2006.01); C12N 5/12 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01)

U.S. Cl. 530—388.25  [530/387.1; 530/387.9; 530/388.1; 530/388.26; 530/389.1; 530/389.3; 424/130.1; 424/139.1; 424/141.1; 424/146.1; 424/158.1; 435/326; 435/338; 435/346]

7 Claims

1. An isolated antibody capable of specifically binding to an isolated polypeptide encoded by a lipase like gene, wherein the polypeptide: (A) binds heparin, (B) has homology with human lipoprotein lipase and hepatic lipase, and (C) comprises a 39 kD catalytic domain of the triacylglycerol lipase family; and wherein the polypeptide comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 8, and SEQ ID NO: 10.