US 7,579,325 B2
	Drugs containing reduced of vitamin B2
Seiichi Araki, Ibaraki-ken (Japan); Mamoru Suzuki, Ibaraki-ken (Japan); Yoshiki Sugihara, Ibaraki-ken (Japan); and Toshio Toyosawa, Ibaraki-ken (Japan)
Assigned to Eisai R & D Management Co., Ltd., Tokyo (Japan)
Appl. No. 10/472,621 PCT Filed Mar. 19, 2002, PCT No. PCT/JP02/02616 § 371(c)(1), (2), (4) Date Sep. 19, 2003, PCT Pub. No. WO02/074313, PCT Pub. Date Sep. 26, 2002.
Claims priority of application No. 2001-080578 (JP), filed on Mar. 21, 2001.
Prior Publication US 2004/0106562 A1, Jun. 03, 2004
Int. Cl. A61K 31/70 (2006.01); A61K 31/495 (2006.01); A61K 31/675 (2006.01)

U.S. Cl. 514—43  [514/250; 514/81]

2 Claims

1. A method for treating sepsis, comprising administering a pharmacologically effective amount of a reduced riboflavin and/or a reduced riboflavin derivative or pharmacologically acceptable salt thereof to a subject in need thereof, wherein the reduced riboflavin is selected from the group consisting of leucoflavin and pharmaceutically acceptable salts thereof, and wherein the reduced riboflavin derivative is selected from the group consisting of leucoflavin mononucleotide, leucoflavin adenine dinucleotide and pharmaceutically acceptable salts thereof.