| US 7,579,169 B2 | ||
| Hereditary hemochromatosis gene | ||
| Winston J. Thomas, San Mateo, Calif. (US); Dennis T. Drayna, Bethesda, Md. (US); John N. Feder, Mountain View, Calif. (US); Andreas Gnirke, San Carlos, Calif. (US); David Ruddy, San Francisco, Calif. (US); Zenta Tsuchihashi, Menlo Park, Calif. (US); and Roger K. Wolff, Mill Valley, Calif. (US) | ||
| Assigned to Bio-Rad Laboratories, Inc., Hercules, Calif. (US) | ||
| Filed on Jan. 05, 2006, as Appl. No. 11/327,689. | ||
| Application 11/327689 is a continuation of application No. 09/497957, filed on Feb. 04, 2000, granted, now 7,078,513. | ||
| Application 09/497957 is a continuation of application No. 08/834497, filed on Apr. 04, 1997, granted, now 6,140,305. | ||
| Application 08/834497 is a continuation in part of application No. 08/652265, filed on May 23, 1996, granted, now 6,025,130. | ||
| Application 08/652265 is a continuation in part of application No. 08/632673, filed on Apr. 16, 1996, granted, now 5,712,098. | ||
| Application 08/632673 is a continuation in part of application No. 08/630912, filed on Apr. 04, 1996, abandoned. | ||
| Prior Publication US 2006/0177854 A1, Aug. 10, 2006 | ||
| Int. Cl. C07H 21/02 (2006.01); C12N 15/00 (2006.01); C12P 21/00 (2006.01); C12N 15/70 (2006.01) | ||
| U.S. Cl. 435—69.1 [435/320.1; 435/252.3; 536/23.5; 536/23.1; 530/350] | 7 Claims |
| 1. A method of producing a mutant HH polypeptide comprising:
(a) transforming isolated host cells with a vector capable of expressing the polypeptide from the nucleic acid sequence as
set forth in SEQ ID NO:10;
(b) culturing the cells under conditions suitable for production of the polypeptide; and
(c) recovering the polypeptide.
|